Here in Ohio Route 40 is very cool. As a child and until now with my wife and children I have loved going to the Ding Ho Chinese Restaurant on West Broad Street in Columbus, Ohio (Hint: Chicken with vegetables, Won Ton Soup and and egg roll). The family that still owns it are really good and fine people.
Near there is the Route 40 Motel. So incredibly ugly/fun architecture that I remember from childhood.